Concepedia

Author

Dirk B. Mendel

Gilead Sciences (United States)

Also Known As

D B Mendel, D Mendel, D. B. MENDEL, D.B. Mendel, DIRK B. MENDEL, Dirk B Mendel, Dirk B. Mendel, Dirk Mendel, Dirk B. Mendel

92

Publications

11.7K

Citations

46

H-Index

81

Concepts

All Affiliations

Gilead Sciences (United States)Dartmouth CollegeHoward Hughes Medical InstituteMaxygen (United States)Roche (United Kingdom)
DB

About

Dirk B. Mendel is an author at Gilead Sciences (United States) specializing in medicine, pharmacology, and cell biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

31

37

7.2K

2

Natural Sciences

10

10

1.4K

3

Biochemistry

10

10

1.1K

4

Health Sciences

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Allergy

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114

Dirk B. Mendel

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65

Publications

11.6K

Citations

46

H-Index

YearCitations

In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.

Dirk B. Mendel, Alexander Laird, Xiaohua Xin,

PubMed

2003

2K

Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site:  Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity

Choung U. Kim, Willard Lew, Matthew A. Williams,

Journal of the American Chemical Society

1997

1.1K

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

Paul A. Khavari, Craig L. Peterson, John W. Tamkun,

Nature

1993

678

A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.

James G. Christensen, Randall Schreck, Jon Burrows,

PubMed

2003

497

The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo

J. Ives, Jackie Carr, Dirk B. Mendel,

Antiviral Research

2002

380

Cytotoxicity of Antiviral Nucleotides Adefovir and Cidofovir Is Induced by the Expression of Human Renal Organic Anion Transporter 1

Edmund Ho, Deborah C. Lin, Dirk B. Mendel,

Journal of the American Society of Nephrology

2000

353

The Antiviral Nucleotide Analogs Cidofovir and Adefovir Are Novel Substrates for Human and Rat Renal Organic Anion Transporter 1

Tomáš Cihlář, Deborah C. Lin, John B. Pritchard,

Molecular Pharmacology

1999

344

HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro.

Dirk B. Mendel, Linda P. Hansen, Mary K. Graves,

Genes & Development

1991

310

Phase I dose-escalating study of SU11654, a small molecule receptor tyrosine kinase inhibitor, in dogs with spontaneous malignancies.

Cheryl A. London, Alison L. Hannah, Regina Zadovoskaya,

PubMed

2003

288

Structure−Activity Relationship Studies of Novel Carbocyclic Influenza Neuraminidase Inhibitors

Choung U. Kim, Willard Lew, Matthew A. Williams,

Journal of Medicinal Chemistry

1998

286

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