D B Barkhimer

1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo

N. Bischofberger, Michael J. M. Hitchcock, M S Chen et al. · Antimicrobial Agents and Chemotherapy · 1994 · 88 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Temperature sensitive shut-off of alphavirus minus strand RNA synthesis maps to a nonstructural protein, nsP4

Dorothea L. Sawicki, D B Barkhimer, Stanley G. Sawicki et al. · Virology · 1990 · 70 citations

Life Sciences, Biology, Molecular Biology +17

Biochemical basis for increased susceptibility to Cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity

Dirk B. Mendel, D B Barkhimer, M S Chen · Antimicrobial Agents and Chemotherapy · 1995 · 51 citations

Life Sciences, Infectious Diseases, Molecular Biology +15