Rosalie C. Sears

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability

Rosalie C. Sears, Faison Nuckolls, Eric B. Haura et al. · Genes & Development · 2000 · 1.4K citations · Full text

Myc Protein Accumulation, Signal Transduction, Cell Regulation +14

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

Elizabeth S. Yeh, Melissa Cunningham, Hugh Arnold et al. · Nature Cell Biology · 2004 · 783 citations

Signal Transduction, Cell Regulation, C-myc Degradation +12

CIP2A Inhibits PP2A in Human Malignancies

Melissa R. Junttila, Pietri Puustinen, Minna Niemelä et al. · Cell · 2007 · 675 citations · Full text

Tumor Biology, Cip2a Inhibits Pp2a, Medicine +5

<i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

Jennifer O’Neil, Jonathan Grim, Peter R. Strack et al. · The Journal of Experimental Medicine · 2007 · 657 citations · Full text

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F

Gustavo Leone, James DeGregori, Rosalie C. Sears et al. · Nature · 1997 · 468 citations

Signal Transduction, Cell Regulation, Biochemistry +12