Shingpan Chan

Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance

Tao Zhang, Rong Qu, Shingpan Chan et al. · Molecular Cancer · 2020 · 143 citations · Full text

Medicine, Oncology, Pharmacology +14

Discovery of JND3229 as a New EGFR^C797S Mutant Inhibitor with In Vivo Monodrug Efficacy

Xiaoyun Lu, Tao Zhang, Sujie Zhu et al. · ACS Medicinal Chemistry Letters · 2018 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +11

GZD824 as a FLT3, FGFR1 and PDGFRα Inhibitor Against Leukemia In Vitro and In Vivo

Yuting Wang, Lenghe Zhang, Xia Tang et al. · Translational Oncology · 2020 · 27 citations · Full text

Medicine, Oncology, Pharmacology +16

Quinolone antibiotic derivatives as new selective Axl kinase inhibitors

Li Tan, Zhang Zhang, Donglin Gao et al. · European Journal of Medicinal Chemistry · 2019 · 26 citations

Medicine, Medicinal Chemistry, Pharmacology +10

2,4-Diarylamino-pyrimidines as kinase inhibitors co-targeting IGF1R and EGFRL858R/T790M

Shingpan Chan, Kun Han, Rong Qu et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 25 citations

Medicine, Medicinal Chemistry, Oncology +10