Thomas Näsström

Extracellular Alpha-Synuclein Oligomers Modulate Synaptic Transmission and Impair LTP Via NMDA-Receptor Activation

Maria José Diógenes, Raquel B. Dias, Diogo M. Rombo et al. · Journal of Neuroscience · 2012 · 271 citations · Full text

Brain Neurons, Synaptic Transmission, Neurotransmitter +22

The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties

Thomas Näsström, Therese Fagerqvist, Mikael Barbu et al. · Free Radical Biology and Medicine · 2010 · 129 citations

Neurodegenerative Diseases, Functional Properties, Biochemistry +10

Monoclonal antibodies selective for α‐synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α‐synuclein transgenic mice with the disease‐causing A30P mutation

Therese Fagerqvist, Veronica Lindström, Eva Nordström et al. · Journal of Neurochemistry · 2013 · 86 citations

Transgenic Mouse Models, Immunology, Neurochemical Biomarkers +20

Antibodies against Alpha-Synuclein Reduce Oligomerization in Living Cells

Thomas Näsström, S. Gonçalves, Charlotte Sahlin et al. · PLoS ONE · 2011 · 74 citations · Full text

Amyloid fibrils prepared using an acetylated and methyl amidated peptide model of the α-Synuclein NAC 71–82 amino acid stretch contain an additional cross-β structure also found in prion proteins

Thomas Näsström, Per Ola Andersson, Christian Lejon et al. · Scientific Reports · 2019 · 57 citations · Full text