Bruno Kyewski

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

Jens Derbinski, Antje Schulte, Bruno Kyewski et al. · Nature Immunology · 2001 · 1K citations

Promiscuous Gene Expression, Lineage Plasticity, Developmental Biology +11

Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

Jens Derbinski, Jana Gäbler, Benedikt Brors et al. · The Journal of Experimental Medicine · 2005 · 537 citations · Full text

Two Genetically Separable Steps in the Differentiation of Thymic Epithelium

Michael Nehls, Bruno Kyewski, Martin Messerle et al. · Science · 1996 · 448 citations

Lineage Plasticity, Cell Lineage, Developmental Biology +15

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells

Ludger Klein, Matthias Klugmann, Klaus-Armin Nave et al. · Nature Medicine · 2000 · 391 citations

Autoimmune Disease, Medicine, Self Protein +8

Medullary Epithelial Cells of the Human Thymus Express a Highly Diverse Selection of Tissue-specific Genes Colocalized in Chromosomal Clusters

Jörn Gotter, Benedikt Brors, Manfred Hergenhahn et al. · The Journal of Experimental Medicine · 2004 · 353 citations · Full text