Leslie Nguyen

PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity

Jing Yuan, Pramod P. Mehta, Min-Jean Yin et al. · Molecular Cancer Therapeutics · 2011 · 159 citations · Full text

Antitumor Activity, Pten Loss, Cancer Biology +22

Metabolism, excretion and pharmacokinetics of [¹⁴C]crizotinib following oral administration to healthy subjects

Theodore R. Johnson, Weiwei Tan, Lance Goulet et al. · Xenobiotica · 2014 · 56 citations

Tumor P-Glycoprotein Correlates with Efficacy of PF-3758309 in in vitro and in vivo Models of Colorectal Cancer

Erica L. Bradshaw‐Pierce, Todd M. Pitts, Aik Choon Tan et al. · Frontiers in Pharmacology · 2013 · 50 citations · Full text

Tumor Xenografts, Chemoprevention Strategy, Tumor P-gp +16

Discovery Pharmacokinetic Studies in Mice Using Serial Microsampling, Dried Blood Spots And Microbore Lc–MS/MS

Sadayappan V. Rahavendran, Sylvia Vekich, Heather Skor et al. · Bioanalysis · 2012 · 48 citations

High-throughput preparative process utilizing three complementary chromatographic purification technologies

Manuel Ventura, William Farrell, Christine M. Aurigemma et al. · Journal of Chromatography A · 2004 · 46 citations

Chemical Engineering, Engineering, Downstream Processing +5