Thomas Hunsaker

Crossinhibitory Activities of Ngn1 and Math1 Allow Specification of Distinct Dorsal Interneurons

Katherine Gowan, Amy W. Helms, Thomas Hunsaker et al. · Neuron · 2001 · 303 citations · Full text

Molecular Neuroscience, Developmental Biology, Cellular Neuroscience +10

An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer

Mark L. McCleland, Adam S. Adler, Yonglei Shang et al. · Cancer Research · 2012 · 195 citations

Systems Biology, Oncology, Engineering +14

Discovery of (<i>S</i>)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1<i>H</i>-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1<i>H</i>)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development

James F. Blake, Michael Burkard, Jocelyn Chan et al. · Journal of Medicinal Chemistry · 2016 · 156 citations · Full text

Erk Kinase Activity, Cellular Pharmacology, Tumor Biology +20

ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma

Ivana Yen, Jeeyun Lee, Yong Sang Hong et al. · Nature · 2021 · 133 citations · Full text

Raf Inhibitor Belvarafenib, Melanoma, Pathology +6

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)

F. Anthony Romero, Jeremy Murray, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2017 · 125 citations · Full text