Sarah J. Kane

Primary structural differences at residue 226 of deer and elk PrP dictate selection of distinct CWD prion strains in gene-targeted mice

Jifeng Bian, Jeffrey R. Christiansen, Julie A. Moreno et al. · Proceedings of the National Academy of Sciences · 2019 · 87 citations · Full text

Creutzfeldt-jakob Disease, Residue 226, Genetics +20

Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein

Jifeng Bian, Sehun Kim, Sarah J. Kane et al. · PLoS Pathogens · 2021 · 85 citations · Full text

Amyloid-β and Proinflammatory Cytokines Utilize a Prion Protein-Dependent Pathway to Activate NADPH Oxidase and Induce Cofilin-Actin Rods in Hippocampal Neurons

Keifer P. Walsh, Laurie S. Minamide, Sarah J. Kane et al. · PLoS ONE · 2014 · 64 citations · Full text

Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice

A. Christy Wyckoff, Sarah J. Kane, Krista Lockwood et al. · Frontiers in Microbiology · 2016 · 27 citations · Full text

PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of prion-infected mice immunotolerant to treatment

Heather Bender, Noelle Noyes, Jessica L. Annis et al. · PLoS ONE · 2019 · 27 citations · Full text

Immunology, Molecular Biology, Antigen Processing +20