SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Carly G.K. Ziegler, Samuel J. Allon, Sarah K. Nyquist, +118

Cell

CellRank for directed single-cell fate mapping

Marius Lange, Volker Bergen, Michal Klein, +9

Nature Methods

Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis

Maximilian Strunz, Lukas M. Simon, Meshal Ansari, +24

Nature Communications

An integrated cell atlas of the lung in health and disease

Lisa Sikkema, Ciro Ramírez-Suástegui, Daniel Strobl, +94

Nature Medicine

An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

Ilias Angelidis, Lukas M. Simon, Isis E. Fernandez, +13

Nature Communications

Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells

Christoph Muus, Malte D. Luecken, Gökcen Eraslan, +98

Inflammatory Lung DiseaseLung InflammationImmunologyViral PathogenesisPathology +14

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

Thomas M. Conlon, Gerrit John-Schuster, Danijela Heide, +45

Nature

Activates Wnt-induced RegenerationLung InflammationMedicineCell BiologyCell Signaling +1

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD

Gizem Günes Günsel, Thomas M. Conlon, Aicha Jeridi, +46

Nature Communications

Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers

Christoph H. Mayr, Lukas M. Simon, Gabriela Leuschner, +20

EMBO Molecular Medicine

An integrated cell atlas of the human lung in health and disease

Lisa Sikkema, Daniel Strobl, Luke Zappia, +66

AsthmaEngineeringAdvanced Lung DiseaseLung InflammationMultiomics +24