Isabelle Pidoux

MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover

Kenn Holmbeck, Paolo Bianco, John J. Caterina et al. · Cell · 1999 · 1.3K citations · Full text

Medicine, Pathobiology, Pathology +12

Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration.

Anthony P. Hollander, Isabelle Pidoux, A Reiner et al. · Journal of Clinical Investigation · 1995 · 487 citations · Full text

Medicine, Orthopaedic Surgery, Pathology +17

Evidence for altered synthesis of type II collagen in patients with osteoarthritis.

Fred R.T. Nelson, Leif Dahlberg, Sheila Laverty et al. · Journal of Clinical Investigation · 1998 · 307 citations · Full text

Medicine, Biochemistry, Orthopaedic Surgery +10

Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13

William Ka Kei Wu, R. Clark Billinghurst, Isabelle Pidoux et al. · Arthritis & Rheumatism · 2002 · 249 citations

Medicine, Orthopaedic Surgery, Pathology +17

The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone

Kenn Holmbeck, Paolo Bianco, Isabelle Pidoux et al. · Journal of Cell Science · 2004 · 228 citations

Medicine, Cell Biology, Bone Metabolism +16