Fred R.T. Nelson

The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration.

John Antoniou, Thomas Steffen, Fred R.T. Nelson et al. · Journal of Clinical Investigation · 1996 · 1K citations · Full text

Medicine, Pathology, Cellular Pathology +7

Evidence for altered synthesis of type II collagen in patients with osteoarthritis.

Fred R.T. Nelson, Leif Dahlberg, Sheila Laverty et al. · Journal of Clinical Investigation · 1998 · 307 citations · Full text

Medicine, Biochemistry, Orthopaedic Surgery +10

Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)

Leif Dahlberg, R. Clark Billinghurst, Paul Manner et al. · Arthritis & Rheumatism · 2000 · 243 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Early post-traumatic osteoarthritis-like changes in human articular cartilage following rupture of the anterior cruciate ligament

Fred R.T. Nelson, R. Clark Billinghurst, Isabelle Pidoux et al. · Osteoarthritis and Cartilage · 2005 · 166 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +14

Glycosaminoglycan Sulfation in Human Osteoarthritis

Anna Plaas, Leigh West, Shirley Wong-Palms et al. · Journal of Biological Chemistry · 1998 · 151 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17