Concepedia

Author

Simone C. Oostindie

Genmab (Netherlands)ORCID

Also Known As

S C Oostindie, Simone C. Oostindie, Simone Oostindie

18

Publications

887

Citations

10

H-Index

12

Concepts

All Affiliations

Genmab (Netherlands)Leiden University Medical CenterLava Therapeutics (Netherlands)University of VirginiaAmsterdam University Medical Centers
SC

About

Simone C. Oostindie is an author at Genmab (Netherlands) specializing in autoimmunity, rheumatoid arthritis, and autoantibodies.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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18

2

Cell Biology

1

1

18

3

Immunology

1

1

18

4

Pathology

1

1

18

5

Rheumatology

1

1

18

Simone C. Oostindie

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9

Publications

651

Citations

9

H-Index

YearCitations

A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface

Rob N. de Jong, Frank J. Beurskens, Sandra Verploegen,

PLoS Biology

2016

218

DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing

Patrick Engelberts, Ida H. Hiemstra, Bart de Jong,

EBioMedicine

2020

159

DuoHexaBody-CD37®, a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies

Simone C. Oostindie, Hilma J. van der Horst, Laurens P. Kil,

Blood Cancer Journal

2020

68

CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering

Simone C. Oostindie, Hilma J. van der Horst, Margaret A. Lindorfer,

Haematologica

2019

61

Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions

Erika M. Cook, Margaret A. Lindorfer, Hilma van der Horst,

The Journal of Immunology

2016

58

Logic-gated antibody pairs that selectively act on cells co-expressing two antigens

Simone C. Oostindie, Derek A. Rinaldi, Gijs G. Zom,

Nature Biotechnology

2022

41

Carbamylation reduces the capacity of IgG for hexamerization and complement activation

Rosalie Lubbers, Simone C. Oostindie, Douwe J. Dijkstra,

Clinical & Experimental Immunology

2019

18

Cyton2: A Model of Immune Cell Population Dynamics That Includes Familial Instructional Inheritance

HoChan Cheon, Andrey Kan, Giulio Prevedello,

Frontiers in Bioinformatics

2021

16

Potent Preclinical Efficacy of DuoHexaBody-CD37 in B-Cell Malignancies

Hilma J. van der Horst, Simone C. Oostindie, Saskia A.G.M. Cillessen,

HemaSphere

2020

12

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