Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

Tomonori Nochi, Yoshikazu Yuki, Haruko Takahashi, +14

Nature Materials

VaccinationNanomedicineCross-protectionAdjuvant-free Intranasal VaccinesImmunology +4

Secretory IgA-mediated protection against<i>V. cholerae</i>and heat-labile enterotoxin-producing enterotoxigenic<i>Escherichia coli</i>by rice-based vaccine

Daisuke Tokuhara, Yoshikazu Yuki, Tomonori Nochi, +9

Proceedings of the National Academy of Sciences

Microbial PathogensImmunologyBacterial PathogensOral ImmunizationEnterotoxigenic Escherichia Coli +14

Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection

Daisuke Tokuhara, Beatriz Álvarez, Mio Mejima, +15

Journal of Clinical Investigation

Microbial PathogensViral DiagnosticsImmunologyViral PathogenesisImmunodominance +14

A Rice-Based Oral Cholera Vaccine Induces Macaque-Specific Systemic Neutralizing Antibodies but Does Not Influence Pre-Existing Intestinal Immunity

Tomonori Nochi, Yoshikazu Yuki, Yuko Katakai, +12

The Journal of Immunology

Transient Elastography-Based Liver Stiffness Age-Dependently Increases in Children

Daisuke Tokuhara, Yuki Cho, Haruo Shintaku

PLoS ONE

Induction of toxin‐specific neutralizing immunity by molecularly uniform rice‐based oral cholera toxin B subunit vaccine without plant‐associated sugar modification

Yoshikazu Yuki, Mio Mejima, Shiho Kurokawa, +18

Plant Biotechnology Journal

Transient Elastography-Based Liver Profiles in a Hospital-Based Pediatric Population in Japan

Yuki Cho, Daisuke Tokuhara, Hiroyasu Morikawa, +8

PLoS ONE

A novel combined adjuvant for nasal delivery elicits mucosal immunity to influenza in aging

Hideki Asanuma, Normaiza Zamri, Shinichi Sekine, +5

Vaccine

VaccinationMucosal VaccinationCross-protectionVaccine DevelopmentImmunology +7

Effects of Citrin Deficiency in the Perinatal Period: Feasibility of Newborn Mass Screening for Citrin Deficiency

Akiko Tamamori, Akie Fujimoto, Yoshiyuki Okano, +21

Pediatric Research

InfertilityNeonatologyMedicinePediatricsPerinatal Period +6

Oral MucoRice expressing double-mutant cholera toxin A and B subunits induces toxin-specific neutralising immunity

Yoshikazu Yuki, Daisuke Tokuhara, Tomonori Nochi, +10

Vaccine

Microbial ToxinB SubunitsToxinologyMucosal ImmunologyVirulence Factor +8