Frédéric Larbret

Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

Issam Ben Sahra, Kathiane Laurent, Sandy Giuliano et al. · Cancer Research · 2010 · 528 citations

Life Sciences, Oncology, Pharmacology +17

Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling

Larissa Lordier, Abdelali Jalil, Frédéric Aurade et al. · Blood · 2008 · 190 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera

Sabrina Dupont, Aline Massé, Chloé James et al. · Blood · 2007 · 188 citations

Medicine, Genetics, Hematology +10

Proplatelet formation is regulated by the Rho/ROCK pathway

Yunhua Chang, Frédéric Aurade, Frédéric Larbret et al. · Blood · 2007 · 169 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +6

FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia

Hana Raslová, Emiko Komura, J P Le Couedic et al. · Journal of Clinical Investigation · 2004 · 169 citations · Full text

Life Sciences, Genetics, Hematology +9