Gladys de Leon Boenig

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

Daniel Lafkas, Amy L. Shelton, Cecilia Chiu et al. · Nature · 2015 · 238 citations

Notch Control, Inflammatory Lung Disease, Lung Inflammation +13

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)

F. Anthony Romero, Jeremy Murray, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2017 · 125 citations · Full text

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

Alexander M. Taylor, Alexandre Côté, Michael C. Hewitt et al. · ACS Medicinal Chemistry Letters · 2016 · 111 citations · Full text

Drug Target, Chemical Biology, Cancer Biology +16

Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300

Terry D. Crawford, F. Anthony Romero, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2016 · 94 citations · Full text

Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action

Olivier René, Benjamin P. Fauber, Gladys de Leon Boenig et al. · ACS Medicinal Chemistry Letters · 2014 · 82 citations · Full text

Rorc Agonists, Minor Structural Change, Pharmacotherapy +19