Sharad Khare

Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid.

D L Earnest, Hana Holubec, Ramesh K. Wali et al. · PubMed · 1994 · 212 citations

Nutrition, Chemoprevention Strategy, Medicine +15

Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta.

Ramesh K. Wali, Brendan P. Frawley, S. Hartmann et al. · PubMed · 1995 · 90 citations

Azoxymethane Model, Oncology, Protein Kinase C +15

Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin.

Ramesh K. Wali, Sharad Khare, Maria Tretiakova et al. · PubMed · 2002 · 88 citations

Acf Development, Oncology, Chemoprevention Strategy +14

1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a noncalcemic analogue of 1 alpha,25-dihydroxyvitamin D3, inhibits azoxymethane-induced colonic tumorigenesis.

Ramesh K. Wali, Marc Bissonnette, Sharad Khare et al. · PubMed · 1995 · 76 citations

Alpha,25-dihydroxyvitamin D3, Medicinal Chemistry, Serum Calcium +15

Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1.

Marc Bissonnette, Sharad Khare, F C von Lintig et al. · PubMed · 2000 · 71 citations

Cyclin D1, Pathology, Cox-2 Expression +17