Brendan P. Frawley

Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta.

Ramesh K. Wali, Brendan P. Frawley, S. Hartmann et al. · PubMed · 1995 · 90 citations

Azoxymethane Model, Oncology, Protein Kinase C +15

1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i

Marc Bissonnette, Xiao-Ying Tien, Sharon M. Niedziela et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1994 · 60 citations

Acute Tpa Pretreatment, Cellular Physiology, Caco-2 Cells +18

Selective preservation of protein kinase C‐ζ in the chemoprevention of azoxymethane‐induced colonic tumors by piroxicam

Hemant K. Roy, Marc Bissonnette, Brendan P. Frawley et al. · FEBS Letters · 1995 · 30 citations · Full text

Chemoprevention Strategy, Pathology, Cell Death +16

TPA causes divergent responses of Ca2+-dependent and Ca2+-independent isoforms of PKC in the nuclei of Caco-2 cells

Brendan P. Frawley, Xiao-Ying Tien, Susanne C. Hartmann et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 1994 · 14 citations

Divergent Responses, Caco-2 Cells, Molecular Physiology +12