Laurence Moss

Tolerance to Opioid‐Induced Respiratory Depression in Chronic High‐Dose Opioid Users: A Model‐Based Comparison With Opioid‐Naïve Individuals

Marijke Hyke Algera, Erik Olofsen, Laurence Moss et al. · Clinical Pharmacology & Therapeutics · 2020 · 54 citations · Full text

Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-tolerant patients

Laurence Moss, Marijke Hyke Algera, Robert L. Dobbins et al. · PLoS ONE · 2022 · 38 citations · Full text

Modeling buprenorphine reduction of fentanyl-induced respiratory depression

Erik Olofsen, Marijke Hyke Algera, Laurence Moss et al. · JCI Insight · 2022 · 33 citations · Full text

Challenging the challenge: A randomized controlled trial evaluating the inflammatory response and pain perception of healthy volunteers after single-dose LPS administration, as a potential model for inflammatory pain in early-phase drug development

Hemme J. Hijma, Laurence Moss, Pim Gal et al. · Brain Behavior and Immunity · 2020 · 19 citations · Full text

A Randomized Trial Assessing the Safety, Pharmacokinetics, and Efficacy During Morning <scp><i>Off</i></scp> of <scp>AZ</scp>‐009

Eva Thijssen, Jonas M. den Heijer, David Puibert et al. · Movement Disorders · 2022 · 19 citations · Full text