Hippo Pathway Activity Influences Liver Cell Fate

Dean Yimlamai, Constantina Christodoulou, Giorgio Giacomo Galli, +7

Cell

Developmental BiologyHepatologyLiver PhysiologyHepatotoxicityLiver Disease +5

Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness

Brenda K. Eustace, Takashi Sakurai, Jean K. Stewart, +11

Nature Cell Biology

Proteomic TechnologyTumor BiologySignaling PathwayMedicineNatural Sciences +12

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

Karen Tumaneng, Karin Schlegelmilch, Ryan C. Russell, +7

Nature Cell Biology

Signal TransductionSignaling PathwayMolecular PathwayMolecular RegulationNatural Sciences +8

Cytokinesis Failure Triggers Hippo Tumor Suppressor Pathway Activation

Neil J. Ganem, Hauke Cornils, Shang-Yi Chiu, +6

Cell

InflammationCytokineImmune Checkpoint InhibitorTumor SuppressorMedicine +3

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

Andrew G. Cox, Katie L. Hwang, Kristin Brown, +18

Nature Cell Biology

Glutamine MetabolismBiosynthesisEngineeringProtein ExpressionBiochemistry +9

Hepatocyte Stress Increases Expression of Yes‐Associated Protein and Transcriptional Coactivator With PDZ‐Binding Motif in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis

Meghan Mooring, Brendan H. Fowl, Shelly Zing Chin Lum, +10

Hepatology

Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma

Apeng Chen, Yinan Jiang, Zhengwei Li, +26

Journal of Clinical Investigation

Myosin 1c and myosin IIB serve opposing roles in lamellipodial dynamics of the neuronal growth cone

Thomas Diefenbach, Vaughan M. Latham, Dean Yimlamai, +3

The Journal of Cell Biology

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

Andrew G. Cox, Allison Tsomides, Dean Yimlamai, +20

The EMBO Journal

Developmental BiologyProtein ExpressionOrgan GrowthGrowth HormoneSustains Nucleotide Synthesis +7

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

Honghai Liu, Cheng–Hai Zhang, Niyatie Ammanamanchi, +32

Science Translational Medicine