Kristin Brown

Sequence analysis of mutations and translocations across breast cancer subtypes

Shantanu Banerji, Kristian Cibulskis, Claudia Rangel‐Escareño et al. · Nature · 2012 · 1.2K citations · Full text

Life Sciences, Genetics, Oncology +17

Tumor immune evasion arises through loss of TNF sensitivity

Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg et al. · Science Immunology · 2018 · 393 citations

Life Sciences, Cancer Biology, Immunology +12

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

Andrew G. Cox, Katie L. Hwang, Kristin Brown et al. · Nature Cell Biology · 2016 · 217 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Adaptive Reprogramming of <i>De Novo</i> Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer

Kristin Brown, Jessica B. Spinelli, John M. Asara et al. · Cancer Discovery · 2017 · 201 citations

Medicine, Oncology, Pharmacology +17

The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

Andrew G. Cox, Kristin Brown, Elias S.J. Arnér et al. · Biochemical Pharmacology · 2008 · 162 citations

Life Sciences, Biochemistry, Cell Biology +13