Kristin Brown

Sequence analysis of mutations and translocations across breast cancer subtypes

Shantanu Banerji, Kristian Cibulskis, Claudia Rangel‐Escareño et al. · Nature · 2012 · 1.2K citations · Full text

Recurrent Mutations, Breast Oncology, Oncology +14

Tumor immune evasion arises through loss of TNF sensitivity

Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg et al. · Science Immunology · 2018 · 384 citations

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

Andrew G. Cox, Katie L. Hwang, Kristin Brown et al. · Nature Cell Biology · 2016 · 210 citations · Full text

Glutamine Metabolism, Biosynthesis, Engineering +11

Adaptive Reprogramming of <i>De Novo</i> Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer

Kristin Brown, Jessica B. Spinelli, John M. Asara et al. · Cancer Discovery · 2017 · 194 citations

The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

Andrew G. Cox, Kristin Brown, Elias S.J. Arnér et al. · Biochemical Pharmacology · 2008 · 160 citations

Inflammation, Reductive Stress, Biochemistry +11