Jessica B. Spinelli

Accumulation of succinate controls activation of adipose tissue thermogenesis

Evanna L. Mills, Kerry A. Pierce, Mark P. Jedrychowski et al. · Nature · 2018 · 528 citations · Full text

Energy Metabolism, Biochemistry, Physiology +6

Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass

Jessica B. Spinelli, Haejin Yoon, Alison E. Ringel et al. · Science · 2017 · 449 citations · Full text

Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation

Noga Ron‐Harel, Daniel Santos, Jonathan M. Ghergurovich et al. · Cell Metabolism · 2016 · 401 citations · Full text

T Cell Activation, Mitochondrial Biogenesis, Mitochondrial Function +7

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

Samuel K. McBrayer, Jared R. Mayers, Gabriel J. DiNatale et al. · Cell · 2018 · 350 citations · Full text

Biochemistry, Medicine, Lipid Peroxidation +9

Oncometabolite <scp>d</scp> -2HG alters T cell metabolism to impair CD8 ⁺ T cell function

Giulia Notarangelo, Jessica B. Spinelli, Elizabeth M. Perez et al. · Science · 2022 · 253 citations · Full text