Dan Sutherlin

Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance

Gerrit J.P. Dijkgraaf, Bruno Alicke, Lasse Weinmann et al. · Cancer Research · 2010 · 363 citations · Full text

Molecular Biology, Glioma, Small Molecule Inhibition +18

Inhibition and Reversal of Myogenic Differentiation by Purine-Based Microtubule Assembly Inhibitors

Omar D. Perez, Young‐Tae Chang, Gustavo R. Rosania et al. · Chemistry & Biology · 2002 · 71 citations · Full text

Myogenic Differentiation, Natural Sciences, Macromolecular Machine +8

Synthesis and structure–activity relationship of N-acyl-Gly-, N-acyl-Sar- and N-blocked-boroPro inhibitors of FAP, DPP4, and POP

Thuy Tran, Clifford Quan, Conrad Yap Edosada et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 53 citations · Full text

Structure–activity Relationship, Medicinal Chemistry, Biochemistry +7

Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers

Michael E. Rothenberg, Michael Tagen, Jae H. Chang et al. · Clinical Drug Investigation · 2019 · 44 citations

Molecular Pharmacology, Medicine, Healthy Volunteers +8