Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy

Christopher E. Nelson, Yaoying Wu, Matthew Gemberling, +9

Nature Medicine

Genome SurgeryGeneticsMolecular BiologyGenetic EngineeringGene Editing +5

Poly(trehalose): Sugar-Coated Nanocomplexes Promote Stabilization and Effective Polyplex-Mediated siRNA Delivery

Antons Sizovs, Lian Xue, Zachary P. Tolstyka, +4

Journal of the American Chemical Society

EngineeringPolymer NanotechnologyCell Culture MediaGene DeliveryBiomedical Engineering +14

A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers

Yaoying Wu, Pamela K. Norberg, Elizabeth A. Reap, +6

ACS Biomaterials Science & Engineering

Glucose-Containing Diblock Polycations Exhibit Molecular Weight, Charge, and Cell-Type Dependence for pDNA Delivery

Yaoying Wu, Miao Wang, Dustin Sprouse, +2

Biomacromolecules

EngineeringGlycobiologyMolecular BiologyCell-type DependenceGene Delivery +18

Self‐Assembling Peptide Gels for 3D Prostate Cancer Spheroid Culture

Kelly M. Hainline, Fangqi Gu, Jacqueline Handley, +5

Macromolecular Bioscience

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

Zachary P. Tolstyka, Haley Phillips, Mallory A. Cortez, +5

ACS Biomaterials Science & Engineering

Comparative study of α-helical and β-sheet self-assembled peptide nanofiber vaccine platforms: influence of integrated T-cell epitopes

Yaoying Wu, Sean H. Kelly, Luis Sánchez-Pérez, +2

Biomaterials Science

Enabling sublingual peptide immunization with molecular self-assemblies

Sean H. Kelly, Yaoying Wu, Ajay K. Varadhan, +3

Biomaterials

Protein FoldingPeptide EngineeringPeptide LibraryImmunologyMolecular Biology +2

Poly(2-deoxy-2-methacrylamido glucopyranose)-<i>b</i>-Poly(methacrylate amine)s: Optimization of Diblock Glycopolycations for Nucleic Acid Delivery

Haibo Li, Mallory A. Cortez, Haley Phillips, +2

ACS Macro Letters

Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8⁺ T‐Cell Responses

Chelsea N. Fries, Yaoying Wu, Sean H. Kelly, +4

Advanced Materials