Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

Sung‐Chun Tang, Thiruma V. Arumugam, X.Z. Shawn Xu, +10

Proceedings of the National Academy of Sciences

Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing

Srinivasulu Chigurupati, Mohamed R. Mughal, Eitan Okun, +5

Biomaterials

Tissue EngineeringEngineeringCutaneous BiologyWound CareWound Healing +7

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

Yoshihiro Kashiwaya, Christian Bergman, Jong‐Hwan Lee, +7

Neurobiology of Aging

Alzheimer's DiseaseBiochemistryMedicineDementiaTau Pathologies +8

Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model

Chiho Hirata‐Fukae, Hui-Fang Li, Hyang-Sook Hoe, +17

Brain Research

Neurodegenerative DiseasesAlzheimer's DiseaseGeneticsDementiaExtensive Amyloid +8

Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke

Thiruma V. Arumugam, Sic L. Chan, Dong‐Gyu Jo, +14

Nature Medicine

ThrombosisIschemic StrokeBrain DysfunctionMedicineCerebrovascular Disease +11

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

Sung‐Chun Tang, Justin D. Lathia, Pradeep Selvaraj, +7

Experimental Neurology

InflammationOxysterolBiochemistryMedicineLipid Peroxidation +8

Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis

Eitan Okun, Kathleen J. Griffioen, Boaz Barak, +8

Proceedings of the National Academy of Sciences

ImmunologyAdult Tlr3-deficient MiceNeuroinflammationToll-like ReceptorsTlr3-deficient Mice +17

Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

Thiruma V. Arumugam, Sung‐Chun Tang, Justin D. Lathia, +12

Proceedings of the National Academy of Sciences

Toll-Like Receptor 3 Is a Negative Regulator of Embryonic Neural Progenitor Cell Proliferation

Justin D. Lathia, Eitan Okun, Sung‐Chun Tang, +9

Journal of Neuroscience

Negative RegulatorInnate Immune SystemImmunologyCell DeathInnate Immunity +19

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

Tae Gen Son, Simonetta Camandola, Thiruma V. Arumugam, +10

Journal of Neurochemistry

Lipid PeroxidationCell DeathNeuroblastoma CellsRedox BiologyCerebral Vascular Regulation +15