Siti Maryam J. M. Yatim

Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer

Yen-An Tang, Yu-feng Chen, Bao Yi et al. · Proceedings of the National Academy of Sciences · 2018 · 267 citations · Full text

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel

Zhen Ning Wee, Siti Maryam J. M. Yatim, Vera Kohlbauer et al. · Nature Communications · 2015 · 169 citations · Full text

Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence

Jian Yuan Goh, Min Feng, Wenyu Wang et al. · Nature Medicine · 2017 · 152 citations

Chromatin, Systems Biology, Breast Cancer Recurrence +14

The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions

Benedict Tan, Siti Maryam J. M. Yatim, Suat Peng et al. · Current Biology · 2020 · 99 citations · Full text

Developmental Biology, Medicine, Epithelial Tight Junctions +12

Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer

Michelle Pek, Siti Maryam J. M. Yatim, Yongjiu Chen et al. · Oncogene · 2017 · 87 citations

Oncology, Viable Therapeutic Strategy, Medicine +7