Yuxian Xiong

The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery

Ziyang Fu, Bin Huang, Jinle Tang et al. · Nature Communications · 2021 · 334 citations · Full text

The SARS-CoV-2 papain-like protease suppresses type I interferon responses by deubiquitinating STING

Dan Cao, Lian Duan, Bin Huang et al. · Science Signaling · 2023 · 55 citations · Full text

USP7 deubiquitinates KRAS and promotes non-small cell lung cancer

Bin Huang, Dan Cao, Xiao Yuan et al. · Cell Reports · 2024 · 19 citations · Full text

The substrate selectivity of papain-like proteases from human-infecting coronaviruses correlates with innate immune suppression

Yuxian Xiong, Bin Huang, Ying Yang et al. · Science Signaling · 2023 · 17 citations

Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8

Yuxin Ye, Yuxian Xiong, Hao Huang · Communications Biology · 2020 · 15 citations · Full text