Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

Irina M. Shapiro, Vihren N. Kolev, Christian M. Vidal, +10

Science Translational Medicine

Cell DeathPathologyCancer BiologyTumor BiologySignaling Pathway +19

Germline Mutation of <i>Bap1</i> Accelerates Development of Asbestos-Induced Malignant Mesothelioma

Jinfei Xu, Yuwaraj Kadariya, Mitchell Cheung, +11

Cancer Research

Bap1 Is a Bona Fide Tumor Suppressor: Genetic Evidence from Mouse Models Carrying Heterozygous Germline <i>Bap1</i> Mutations

Yuwaraj Kadariya, Mitchell Cheung, Jinfei Xu, +7

Cancer Research

Cancer SusceptibilityTumor BiologySomatic VariantAsbestos ExposureTumor Heterogeneity +12

Inflammation-Related IL1β/IL1R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma

Yuwaraj Kadariya, Craig W. Menges, Jacqueline Talarchek, +8

Cancer Prevention Research

ImmunotoxicologyLung InflammationImmunologyPathologyCancer Biology +14

Tumor Suppressor Alterations Cooperate to Drive Aggressive Mesotheliomas with Enriched Cancer Stem Cells via a p53–miR-34a–c-Met Axis

Craig W. Menges, Yuwaraj Kadariya, Deborah A. Altomare, +9

Cancer Research

PathologyCancer BiologyTumor BiologyDrive Aggressive MesotheliomasTail Vein Injections +14

Inactivation of <i>Bap1</i> Cooperates with Losses of <i>Nf2</i> and <i>Cdkn2a</i> to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models

Anna-Mariya Kukuyan, Eleonora Sementino, Yuwaraj Kadariya, +9

Cancer Research

Mice Heterozygous for Germ-line Mutations in Methylthioadenosine Phosphorylase ( <i>MTAP</i> ) Die Prematurely of T-Cell Lymphoma

Yuwaraj Kadariya, Bu Yin, Baiqing Tang, +8

Cancer Research

Germline BAP1 mutation in a family with high incidence of multiple primary cancers and a potential gene–environment interaction

Mitchell Cheung, Yuwaraj Kadariya, Jacqueline Talarchek, +4

Cancer Letters

Potential Gene–environment InteractionCancer EpidemiologyGermline Bap1 MutationMultiple Primary CancersMedicine +8

Thymine DNA glycosylase as a novel target for melanoma

Pietro Mancuso, Rossella Tricarico, Vikram Bhattacharjee, +19

Oncogene

The methionine salvage pathway compound 4-methylthio-2-oxobutanate causes apoptosis independent of down-regulation of ornithine decarboxylase

Baiqing Tang, Yuwaraj Kadariya, Maureen E. Murphy, +1

Biochemical Pharmacology

Reductive Stress4-Methylthio-2-oxobutanate CausesBiochemistryMedicineLipid Peroxidation +8