Deborah A. Fraser

A Dramatic Increase of C1q Protein in the CNS during Normal Aging

Alexander Stephan, Daniel V. Madison, José Marı́a Mateos et al. · Journal of Neuroscience · 2013 · 420 citations · Full text

C1q Protein Levels, Synapse Elimination, C1q-deficient Mice +25

Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells

Marie Benoit, Elizabeth Clarke, Pedro Morgado et al. · The Journal of Immunology · 2012 · 236 citations · Full text

C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production

Deborah A. Fraser, Karntipa Pisalyaput, Andrea J. Tenner · Journal of Neurochemistry · 2009 · 198 citations · Full text

C1q Differentially Modulates Phagocytosis and Cytokine Responses during Ingestion of Apoptotic Cells by Human Monocytes, Macrophages, and Dendritic Cells

Deborah A. Fraser, Amanda K. Laust, Edward L. Nelson et al. · The Journal of Immunology · 2009 · 156 citations · Full text

C1q Bound, Immune Regulation, Immunology +22

C1q and MBL, components of the innate immune system, influence monocyte cytokine expression

Deborah A. Fraser, Suzanne S. Bohlson, Nijole Jasinskiene et al. · Journal of Leukocyte Biology · 2006 · 139 citations

C1q Knockout Mice, Defense Collagen Family, Innate Immune System +16