Robert D. Giacometti

Structure‐Based Design of a Highly Constrained Nucleic Acid Analogue: Improved Duplex Stabilization by Restricting Sugar Pucker and Torsion Angle <i>γ</i>

Stephen Hanessian, Benjamin R. Schroeder, Robert D. Giacometti et al. · Angewandte Chemie International Edition · 2012 · 35 citations · Full text

Design, synthesis, and duplex-stabilizing properties of conformationally constrained tricyclic analogues of LNA

Robert D. Giacometti, Juan C. Salinas, Michael E. Østergaard et al. · Organic & Biomolecular Chemistry · 2016 · 20 citations

A Constrained Tricyclic Nucleic Acid Analogue of α-<scp>l</scp>-LNA: Investigating the Effects of Dual Conformational Restriction on Duplex Thermal Stability

Stephen Hanessian, Jernej Wagger, Bradley L. Merner et al. · The Journal of Organic Chemistry · 2013 · 20 citations

Molecular Biology, Oligonucleotide Sequences, Constrained Tricyclic Analogue +16

Heteroatom Analogues of Hydrocodone: Synthesis and Biological Activity

Robert D. Giacometti, Jan Duchek, Lukáš Werner et al. · The Journal of Organic Chemistry · 2013 · 16 citations

Medicinal Chemistry, Derivative (Chemistry), Bioorganic Chemistry +13

Synthesis of Polycyclic Indolone and Pyrroloindolone Heterocycles via the Annulation of Indole- and Pyrrole-2-Carboxylate Esters with Arynes

Yeeman K. Ramtohul, Robert D. Giacometti · Synlett · 2009 · 14 citations

Heterocyclic, Pyrrole-2-carboxylate Esters, Diversity-oriented Synthesis +8