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Synthesis of Polycyclic Indolone and Pyrroloindolone Heterocycles via the Annulation of Indole- and Pyrrole-2-Carboxylate Esters with Arynes
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2009
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HeterocyclicPyrrole-2-carboxylate EstersDiversity-oriented SynthesisPyrroloindolone HeterocyclesOrganic ChemistryStereoselective SynthesisHeterocycle ChemistryPolycyclic IndoloneGeneral MethodPharmacologySynthetic Chemistry
A mild and general method for the synthesis of a variety of polycyclic indolone and pyrroloindolone heterocycles via the reaction of indole- and pyrrole-2-carboxylate esters with arynes has been developed.