Long P. Le

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai, Zongli Zheng, Nathalie T. Nguyen et al. · Nature Biotechnology · 2014 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Crizotinib in <i>ROS1</i>-Rearranged Non–Small-Cell Lung Cancer

Alice T. Shaw, Sai‐Hong Ignatius Ou, Yung‐Jue Bang et al. · New England Journal of Medicine · 2014 · 2K citations

Medicine, Oncology, Pharmacology +17

Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in <i>ALK</i> -Rearranged Lung Cancer

Justin F. Gainor, Leila Dardaei, Satoshi Yoda et al. · Cancer Discovery · 2016 · 1.1K citations · Full text

Medicine, Oncology, Pharmacology +10

Towards a general-purpose foundation model for computational pathology

Richard J. Chen, Tong Ding, Ming Y. Lu et al. · Nature Medicine · 2024 · 1.1K citations · Full text

Medicine, Biomedical Informatics, Pathology +13

Anchored multiplex PCR for targeted next-generation sequencing

Zongli Zheng, Matthew Liebers, Boryana Zhelyazkova et al. · Nature Medicine · 2014 · 917 citations · Full text

Life Sciences, Biology, Molecular Biology +9