Regina M. Young

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

Joseph A. Fraietta, Simon F. Lacey, Elena J. Orlando et al. · Nature Medicine · 2018 · 1.8K citations · Full text

Life Sciences, Immunology, Oncology +16

CRISPR-engineered T cells in patients with refractory cancer

Edward A. Stadtmauer, Joseph A. Fraietta, Megan M. Davis et al. · Science · 2020 · 1.4K citations · Full text

Life Sciences, Biotechnology, Immunology +17

Decade-long leukaemia remissions with persistence of CD4+ CAR T cells

J. Joseph Melenhorst, Gregory M. Chen, Meng Wang et al. · Nature · 2022 · 920 citations · Full text

Life Sciences, Hematology, Immunology +14

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

Joseph A. Fraietta, Christopher L. Nobles, Morgan A. Sammons et al. · Nature · 2018 · 861 citations · Full text

Life Sciences, Cell Biology, Immunology +14

B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma

Adam D. Cohen, Alfred L. Garfall, Edward A. Stadtmauer et al. · Journal of Clinical Investigation · 2019 · 790 citations · Full text

Life Sciences, Hematology, Immunology +17