Vinod F. Patel

LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.

C Shih, V J Chen, Lynn S. Gossett et al. · PubMed · 1997 · 565 citations

Medicine, Medicinal Chemistry, Pharmacology +14

AMG 706, an Oral, Multikinase Inhibitor that Selectively Targets Vascular Endothelial Growth Factor, Platelet-Derived Growth Factor, and Kit Receptors, Potently Inhibits Angiogenesis and Induces Regression in Tumor Xenografts

Anthony Polverino, Angela Coxon, Charlie Starnes et al. · Cancer Research · 2006 · 283 citations · Full text

Medicine, Oncology, Pharmacology +15

Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors

Michele Potashman, James Bready, Angela Coxon et al. · Journal of Medicinal Chemistry · 2007 · 167 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Quantification of Tricuspid Regurgitation by Live Three‐Dimensional Transthoracic Echocardiographic Measurements of Vena Contracta Area

Dasan E. Velayudhan, Todd M. Brown, Navin C. Nanda et al. · Echocardiography · 2006 · 162 citations

Medicine, Cardiology, Diagnostic Imaging +16

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Gejing Deng, Junqing Shen, Ming Yin et al. · Journal of Biological Chemistry · 2014 · 137 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17