Gejing Deng

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

Kensuke Tateishi, Hiroaki Wakimoto, A. John Iafrate et al. · Cancer Cell · 2015 · 445 citations · Full text

Medicine, Cancer Biology, Oncology +16

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

Ling Xu, Amarendra Pegu, Ercole Rao et al. · Science · 2017 · 271 citations · Full text

Pharmacy, Immunology, Infectious Diseases +17

Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

Lan Wu, Edward Seung, Ling Xu et al. · Nature Cancer · 2019 · 250 citations

Life Sciences, Immunology, Oncology +16

Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

Michael Lampa, Heike Arlt, Timothy He et al. · PLoS ONE · 2017 · 168 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +17

A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells

Edward Seung, Zhen Xing, Lan Wu et al. · Nature · 2022 · 152 citations

Medicine, Cancer Biology, Oncology +17