A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding

Rahmad Akbar, Philippe A. Robert, Milena Pavlović, +12

Cell Reports

In silico proof of principle of machine learning-based antibody design at unconstrained scale

Rahmad Akbar, Philippe A. Robert, Cédric R. Weber, +16

mAbs

EngineeringMachine LearningArtificial Immune SystemImmunologyImmunological Computing +15

The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires

Milena Pavlović, Lonneke Scheffer, Keshav Motwani, +39

Nature Machine Intelligence

Unconstrained generation of synthetic antibody–antigen structures to guide machine learning methodology for antibody specificity prediction

Philippe A. Robert, Rahmad Akbar, Robert Frank, +22

Nature Computational Science

Artificial IntelligenceSynthetic Antibody–antigen StructuresMachine LearningEngineeringAntibody Specificity Prediction +10

Individualized VDJ recombination predisposes the available Ig sequence space

Andrei Slabodkin, Maria Chernigovskaya, Ivana Mikocziova, +13

Genome Research

GeneticsImmunologyGenetic EpidemiologyGenomicsSequence Design +16

Simple computational methods can outperform deep learning in designing diverse, binder-enriched antibody libraries

Lewis Chinery, Alissa M. Hummer, Brij Bhushan Mehta, +8

Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for real-world antibody specificity prediction

Philippe A. Robert, Rahmad Akbar, Robert Frank, +22

Artificial IntelligenceEngineeringMachine LearningArtificial Immune SystemImmunology +18

In silico proof of principle of machine learning-based antibody design at unconstrained scale

Rahmad Akbar, Philippe A. Robert, Cédric R. Weber, +16

Feasible Transfer LearningEngineeringMachine LearningArtificial Immune SystemImmunology +16

A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding

Rahmad Akbar, Philippe A. Robert, Milena Pavlović, +12

Repository for Publications and Research Data (ETH Zurich)

Compact VocabularyAntibody-antigen BindingMachine LearningEngineeringParatope-epitope Interactions +20

immuneML: an ecosystem for machine learning analysis of adaptive immune receptor repertoires

Milena Pavlović, Lonneke Scheffer, Keshav Motwani, +40

EngineeringMachine LearningAdaptive Immune SystemArtificial Immune SystemImmunology +14