Tammie K. Jinkerson

Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain:  Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties

Arthur Gomtsyan, Erol K. Bayburt, Robert G. Schmidt et al. · Journal of Medicinal Chemistry · 2005 · 163 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

α-Methylation at benzylic fragment of N-aryl-N′-benzyl ureas provides TRPV1 antagonists with better pharmacokinetic properties and higher efficacy in inflammatory pain model

Arthur Gomtsyan, Erol K. Bayburt, Ryan G. Keddy et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 33 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Structure–activity studies of a novel series of 5,6-fused heteroaromatic ureas as TRPV1 antagonists

Irene Drizin, Arthur Gomtsyan, Erol K. Bayburt et al. · Bioorganic & Medicinal Chemistry · 2006 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

In Vitro Structure−Activity Relationship and In Vivo Characterization of 1-(Aryl)-3-(4-(amino)benzyl)urea Transient Receptor Potential Vanilloid 1 Antagonists

Richard J. Perner, Stanley DiDomenico, John R. Koenig et al. · Journal of Medicinal Chemistry · 2007 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A‐272651, a nonpeptidic blocker of large‐conductance Ca²⁺‐activated K⁺channels, modulates bladder smooth muscle contractility and neuronal action potentials

Shieh Cc, S. Turner, X.-F Zhang et al. · British Journal of Pharmacology · 2007 · 11 citations · Full text

Life Sciences, Pharmacology, Physiology +17