Jonathan A. Kirk

Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

Dong I. Lee, Guangshuo Zhu, Takashi Sasaki et al. · Nature · 2015 · 343 citations · Full text

Molecular Physiology, Disease Mechanism, Medicine +5

Multiple Reaction Monitoring to Identify Site-Specific Troponin I Phosphorylated Residues in the Failing Human Heart

Pingbo Zhang, Jonathan A. Kirk, Weihua Ji et al. · Circulation · 2012 · 140 citations · Full text

Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis–Associated Versus Idiopathic Pulmonary Arterial Hypertension

Steven Hsu, Kristen M. Kokkonen-Simon, Jonathan A. Kirk et al. · Circulation · 2018 · 140 citations · Full text

Creatine kinase–mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved

Ashish Gupta, Ashwin Akki, Yibin Wang et al. · Journal of Clinical Investigation · 2011 · 138 citations · Full text

Cardiac Muscle, Heart Failure, Causal Evidence +25

Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover

Thomas G. Martin, Valerie D. Myers, Praveen Kumar Dubey et al. · Nature Communications · 2021 · 114 citations · Full text