Creatine kinase–mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved

Ashish Gupta, Ashwin Akki, Yibin Wang, +12

Journal of Clinical Investigation

Cardiac MuscleHeart FailureCausal EvidenceCardiac RegenerationMetabolic Remodeling +23

Compensated cardiac hypertrophy is characterised by a decline in palmitate oxidation

Ashwin Akki, Katie Smith, Anne‐Marie L. Seymour

Molecular and Cellular Biochemistry

Palmitate OxidationCardiac MuscleCardiomyopathyHeart FailureBiochemistry +11

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216

Dinesh Thummuri, Sajid Khan, Patrick W. Underwood, +15

Molecular Cancer Therapeutics

Skeletal muscle ATP kinetics are impaired in frail mice

Ashwin Akki, Huanle Yang, Ashish Gupta, +6

AGE

Frail MiceMuscle FunctionSkeletal MusclePhysiologyApplied Physiology +3

Impaired ATP Kinetics in Failing In Vivo Mouse Heart

Ashish Gupta, V. P. Chacko, Michael Schär, +2

Circulation Cardiovascular Imaging

Reduced in vivo high-energy phosphates precede Adriamycin-induced cardiac dysfunction

M. Yu. Maslov, V. P. Chacko, Glenn A. Hirsch, +4

American Journal of Physiology-Heart and Circulatory Physiology

Cardiac MuscleHeart FailureCardiovascular PharmacologyPharmacotherapyCardiovascular Toxicity +14

Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy

Ashwin Akki, A.-M. L. Seymour

Cardiovascular Research

Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium

Ashwin Akki, Jason Su, Toshiyuki Yano, +6

American Journal of Physiology-Heart and Circulatory Physiology

Effect of endoscopic submucosal dissection on histologic diagnosis in Barrett’s esophagus visible neoplasia

Dennis Yang, William King, Hiroyuki Aihara, +16

Gastrointestinal Endoscopy

EsophagusEsophageal CancerMedicineHistologic DiagnosisHistopathology +10

Pseudoangiosarcomatous Urothelial Carcinoma of the Urinary Bladder

Gladell P. Paner, Roni M. Cox, Kyle A. Richards, +6

The American Journal of Surgical Pathology

Pseudoangiosarcomatous PatternUrologyTumoral PathologyGenitourinary CancerSurgical Pathology +7