Maria Laura Pati

Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1

Maria Laura Pati, Diana Groza, Chiara Riganti et al. · Pharmacological Research · 2016 · 42 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Multifunctional thiosemicarbazones and deconstructed analogues as a strategy to study the involvement of metal chelation, Sigma-2 (σ2) receptor and P-gp protein in the cytotoxic action: In vitro and in vivo activity in pancreatic tumors

Maria Laura Pati, Mauro Niso, Dirk Spitzer et al. · European Journal of Medicinal Chemistry · 2017 · 40 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer

Maria Laura Pati, John R. Hornick, Mauro Niso et al. · BMC Cancer · 2017 · 39 citations · Full text

Medicine, Oncology, Pharmacology +13

Novel and Selective Fluorescent σ₂‐Receptor Ligand with a 3,4‐Dihydroisoquinolin‐1‐one Scaffold: A Tool to Study σ₂ Receptors in Living Cells

Mauro Niso, Chiara Riganti, Maria Laura Pati et al. · ChemBioChem · 2015 · 26 citations

Medicine, Oncology, Pharmacology +16

Novel metal chelators thiosemicarbazones with activity at the σ₂receptors and P-glycoprotein: an innovative strategy for resistant tumor treatment

Maria Laura Pati, Mauro Niso, Savina Ferorelli et al. · RSC Advances · 2015 · 24 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15