Dirk Spitzer

C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy

Anna Richards, Arn M. J. M. van den Maagdenberg, Joanna C. Jen et al. · Nature Genetics · 2007 · 444 citations

Ocular Disease, C-terminal Truncations, Retina +8

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site

Jinbin Xu, Chenbo Zeng, Wenhua Chu et al. · Nature Communications · 2011 · 295 citations · Full text

Protein Function, Signal Transduction, Molecular Physiology +10

Properdin Can Initiate Complement Activation by Binding Specific Target Surfaces and Providing a Platform for De Novo Convertase Assembly

Dirk Spitzer, Lynne M. Mitchell, John P. Atkinson et al. · The Journal of Immunology · 2007 · 278 citations · Full text

Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation

Dirk Spitzer, Juan-Carlos Murciano, Bi‐Sen Ding et al. · Blood · 2010 · 99 citations

The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine

John R. Hornick, Jinbin Xu, Suwanna Vangveravong et al. · Molecular Cancer · 2010 · 78 citations · Full text