Allison Carles

Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition <i>in Vitro</i> and Enable Restoration of Cognition in an Alzheimer’s Disease Mouse Model upon Irradiation

Matthias Scheiner, Alexandra Sink, Matthias Hoffmann et al. · Journal of the American Chemical Society · 2022 · 51 citations

Medicine, Neuroscience, Pharmacology +14

Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer’s Disease Mouse Model

Philipp Spatz, Sophie A. M. Steinmüller, Anna Tutov et al. · Journal of Medicinal Chemistry · 2023 · 27 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Targeting N-Methyl-d-Aspartate Receptors in Neurodegenerative Diseases

Allison Carles, Aline Freyssin, Florent Perin-Dureau et al. · International Journal of Molecular Sciences · 2024 · 27 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The selective butyrylcholinesterase inhibitor UW‐MD‐95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease

Allison Carles, Matthias Hoffmann, Matthias Scheiner et al. · CNS Neuroscience & Therapeutics · 2024 · 16 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Exposure of R6/2 mice in an enriched environment augments P42 therapy efficacy on Huntington's disease progression

Simon Couly, Allison Carles, Morgane Denus et al. · Neuropharmacology · 2021 · 15 citations

Life Sciences, Neurobiology, Neuroscience +13