Simon Couly

Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice

Alistair T. Pagnamenta, Pierre Heemeryck, Hilary C. Martin et al. · Human Molecular Genetics · 2019 · 65 citations · Full text

Neuropsychology, Brain Function, Brain Development +24

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

Lucie Crouzier, Alberto Danese, Yuko Yasui et al. · Science Translational Medicine · 2022 · 64 citations · Full text

Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis

Simon Couly, Bilal Khalil, Véronique Viguier et al. · Human Molecular Genetics · 2019 · 35 citations · Full text

Sigma-1 (σ1) receptor activity is necessary for physiological brain plasticity in mice

Lucie Crouzier, Simon Couly, Chloé Roques et al. · European Neuropsychopharmacology · 2020 · 31 citations · Full text

Synaptic Plasticity, Receptor Activity, Molecular Neuroscience +11

Improvement of BDNF signalling by P42 peptide in Huntington's disease

Simon Couly, Alexia Paucard, Nathalie Bonneaud et al. · Human Molecular Genetics · 2018 · 22 citations · Full text

P42 Peptide, Bdnf Deficit, Medicine +12