Matthias Scheiner

Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer’s Disease Mouse Model

Matthias Hoffmann, Carina Stiller, Erik Endres et al. · Journal of Medicinal Chemistry · 2019 · 85 citations · Full text

Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects <i>In Vitro</i> and Neuroprotective Effects in a Pharmacological Alzheimer’s Disease Mouse Model

Feng He, C. James Chou, Matthias Scheiner et al. · Journal of Medicinal Chemistry · 2021 · 57 citations · Full text

Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition <i>in Vitro</i> and Enable Restoration of Cognition in an Alzheimer’s Disease Mouse Model upon Irradiation

Matthias Scheiner, Alexandra Sink, Matthias Hoffmann et al. · Journal of the American Chemical Society · 2022 · 49 citations

Dual-Acting Cholinesterase–Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo

Matthias Scheiner, Dominik Dolles, Sandra Gunesch et al. · Journal of Medicinal Chemistry · 2019 · 45 citations · Full text

Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer’s Disease Mouse Model

Matthias Scheiner, Matthias Hoffmann, Feng He et al. · Journal of Medicinal Chemistry · 2021 · 43 citations · Full text