Sandra Gunesch

Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer’s Disease Mouse Model

Matthias Hoffmann, Carina Stiller, Erik Endres et al. · Journal of Medicinal Chemistry · 2019 · 89 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

7-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory impairment in vivo

Sandra Gunesch, Matthias Hoffmann, Carolina Kiermeier et al. · Redox Biology · 2019 · 82 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles

Dominik Dolles, Matthias Hoffmann, Sandra Gunesch et al. · Journal of Medicinal Chemistry · 2018 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects <i>In Vitro</i> and Neuroprotective Effects in a Pharmacological Alzheimer’s Disease Mouse Model

Feng He, C. James Chou, Matthias Scheiner et al. · Journal of Medicinal Chemistry · 2021 · 59 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

One Enzyme, Three Metabolites: Shewanella algae Controls Siderophore Production via the Cellular Substrate Pool

Sina Rütschlin, Sandra Gunesch, Thomas Böttcher · Cell chemical biology · 2017 · 56 citations · Full text

Life Sciences, Biochemistry, Microbiology +11