Erik Endres

Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer’s Disease Mouse Model

Matthias Hoffmann, Carina Stiller, Erik Endres et al. · Journal of Medicinal Chemistry · 2019 · 85 citations · Full text

Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition <i>in Vitro</i> and Enable Restoration of Cognition in an Alzheimer’s Disease Mouse Model upon Irradiation

Matthias Scheiner, Alexandra Sink, Matthias Hoffmann et al. · Journal of the American Chemical Society · 2022 · 49 citations

Photopharmacology on Acetylcholinesterase: Novel Photoswitchable Inhibitors with Improved Pharmacological Profiles

Matthias Scheiner, Alexandra Sink, Philipp Spatz et al. · ChemPhotoChem · 2020 · 23 citations · Full text

Novel Photoswitchable Inhibitors, Bistacrine Ache Inhibitor, H Ache +19

Structural basis for the bi-specificity of USP25 and USP28 inhibitors

J. Patzke, Florian Sauer, Radhika K. Nair et al. · EMBO Reports · 2024 · 13 citations · Full text

Usp28 Inhibitors, Medicinal Chemistry, Drug Target +10

Warhead Reactivity Limits the Speed of Inhibition of the Cysteine Protease Rhodesain

Patrick Johé, Sascha Jung, Erik Endres et al. · ACS Chemical Biology · 2021 · 11 citations

Molecular Biology, Chemical Biology, Warhead Reactivity Limits +16