Chrysovalantou E. Xirouchaki

PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity

Florian Wiede, Kun‐Hui Lu, Xin Du et al. · Cancer Discovery · 2021 · 137 citations · Full text

Life Sciences, Immunology, Oncology +17

Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance

Chrysovalantou E. Xirouchaki, Yaoyao Jia, Meagan J. McGrath et al. · Science Advances · 2021 · 105 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity

Garron T. Dodd, Chrysovalantou E. Xirouchaki, Matthew J. Eramo et al. · Cell Reports · 2019 · 94 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Impaired glucose metabolism and exercise capacity with muscle-specific glycogen synthase 1 (gys1) deletion in adult mice

Chrysovalantou E. Xirouchaki, Salvatore Mangiafico, Katherine Bate et al. · Molecular Metabolism · 2016 · 66 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity

Spencer Greatorex, Supreet Kaur, Chrysovalantou E. Xirouchaki et al. · Journal of Clinical Investigation · 2023 · 49 citations · Full text

Veterinary Medicine, Cell Biology, Pathobiology +17