Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

Sandie Tuduri, Laure Crabbé, Chiara Conti, +11

Nature Cell Biology

ChromatinGenome InstabilityChromatin RemodelingNatural SciencesGenetics +8

DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2

Agata Smogorzewska, Jan Karlseder, Heidi Holtgreve-Grez, +2

Current Biology

ChromatinGenome InstabilityGeneticsGenomic MechanismMolecular Biology +6

Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor

Kurt Schönfeld, Christiane Sahm, Congcong Zhang, +18

Molecular Therapy

Telomere dysfunction as a cause of genomic instability in Werner syndrome

Laure Crabbé, Anna Jauch, Colleen M. Naeger, +2

Proceedings of the National Academy of Sciences

ChromatinGenome InstabilityWerner SyndromeMendelian DisorderGenetic Disorder +11

Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas.

Thomas Ried, K E Just, Heidi Holtgreve-Grez, +7

PubMed

Gene AmplificationBreast OncologyCancer PathologyCytogeneticsGenetics +18

Mapping of multiple DNA gains and losses in primary small cell lung carcinomas by comparative genomic hybridization

Thomas Ried, Iver Petersen, Heidi Holtgreve-Grez, +4

Lung Cancer

Somatic VariantTumor HeterogeneityMedicineGeneticsMultiple Dna Gains +7

Molecular cytogenetic analysis of formalin-fixed, paraffin-embedded solid tumors by comparative genomic hybridization after universal DNA-amplification

Michael R. Spelcher, Stanislas du Manoir, Evelin Schröck, +5

Human Molecular Genetics

Possible role for salivary gland protein in taste reception indicated by homology to lipophilic-ligand carrier proteins

Hartwig Schmale, Heidi Holtgreve-Grez, Heidje Christiansen

Nature

Signal TransductionBiochemistryNatural SciencesMolecular BiologySalivary Gland Protein +2

Comparison of DNA gains and losses in primary renal clear cell carcinomas and metastatic sites: importance of 1q and 3p copy number changes in metastatic events.

Jacek Gronwald, Stefan Störkel, Heidi Holtgreve-Grez, +5

PubMed

CytogeneticsMetastatic TumorsRenal PathologyComparative Genomic HybridizationPathology +16

Separate and variably shaped chromosome arm domains are disclosed by chromosome arm painting in human cell nuclei

Steffen Dietzel, Anna Jauch, Dirk Kienle, +8

Chromosome Research