Meriem Hasmim

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

Muhammad Zaeem Noman, Giacomo Desantis, Bassam Janji et al. · The Journal of Experimental Medicine · 2014 · 2.1K citations · Full text

Medicine, Immunology, Oncology +16

Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from T-cell–Mediated Lysis

Intissar Akalay, Bassam Janji, Meriem Hasmim et al. · Cancer Research · 2013 · 296 citations

Medicine, Cancer Biology, Oncology +17

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200

Muhammad Zaeem Noman, Bassam Janji, Abdérémane Abdou et al. · OncoImmunology · 2017 · 252 citations · Full text

Medicine, Molecular Biology, Oncology +17

Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy

Muhammad Zaeem Noman, Santiago Parpal, Kris Van Moer et al. · Science Advances · 2020 · 251 citations · Full text

Medicine, Immunology, Oncology +17

The Cooperative Induction of Hypoxia-Inducible Factor-1α and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis

Muhammad Zaeem Noman, Stéphanie Buart, Jos van Pelt et al. · The Journal of Immunology · 2009 · 176 citations · Full text

Medicine, Cancer Biology, Oncology +14