Muhammad Zaeem Noman

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

Muhammad Zaeem Noman, Giacomo Desantis, Bassam Janji et al. · The Journal of Experimental Medicine · 2014 · 2.1K citations · Full text

Mdscs Il-6, Immunology, Cell Death +21

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

Joanna Bagińska, Elodie Viry, Guy Berchem et al. · Proceedings of the National Academy of Sciences · 2013 · 321 citations · Full text

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

Guy Berchem, Muhammad Zaeem Noman, Manon Bosseler et al. · OncoImmunology · 2015 · 306 citations · Full text

Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from T-cell–Mediated Lysis

Intissar Akalay, Bassam Janji, Meriem Hasmim et al. · Cancer Research · 2013 · 291 citations

Breast Oncology, Immunology, Immunoediting +19

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200

Muhammad Zaeem Noman, Bassam Janji, Abdérémane Abdou et al. · OncoImmunology · 2017 · 244 citations · Full text